Wu Wutong, male, from Zhangzhou, Fujian, born in August 1937, Han nationality, member of the Communist Party of China. Graduated from Nanjing College of Pharmacy (now China Pharmaceutical University) in 1959. After staying in school to teach. He has served as the director of the Biochemistry Teaching and Research Section, the Biotechnology Center, the Marine Medicine Research Center, the dean of the School of Biopharmaceuticals, a professor, and a doctoral supervisor. He was a visiting professor at the University of Illinois, the University of Texas, and the Health Science Research Center. He is also a member of the Disciplinary Evaluation Group of the Academic Degrees Committee of the State Council, the vice chairman of the Biochemical and Biotechnology Drug Professional Committee of the Chinese Pharmaceutical Association, a national new drug review expert, the chairman of the Jiangsu Biotechnology Association, and the chairman of the Jiangsu Biochemistry and Molecular Biology Society. He was once elected as a representative of the People's Congress of Jiangsu Province and a representative of the People's Congress of Gulou District, Nanjing.
Research results
Wu Wutong has made outstanding contributions to the development of pharmaceutical science and biopharmaceutical industry, and formed a research direction with innovative characteristics. Has undertaken and completed 8 national key scientific and technological research projects of the "Eighth Five-Year Plan" and "Ninth Five-Year Plan", 1 marine technology project of the "863" Plan and 1 project of the "973" Plan, 3 natural science fund projects, and new drug research fund projects 2 items, 1 item each for the Ministry of Education's Innovative Talent Fund Project and 1 Ph.D. Authorization Program, "Eighth Five-Year Plan" Jiangsu Province Key Scientific and Technological Research Projects and 3 Natural Science Funding Projects, and 4 Applied Basic Research Funding Projects. He in-depth study of the cloning and expression of natural active substances and their functional genes, and then discovering and researching new drugs, exploring an effective way to create new biotechnology drugs. More than 10 new biochemical drugs have been successfully developed, among which elastase, kallikrein and thrombin have been widely used. He successfully constructed a polypeptide protein secretion expression system, which became an effective expression technology platform for genetic engineering polypeptide drugs; he developed recombinant hirudin III and other protein engineering drugs with independent intellectual property rights. He used the "VEGF-183" discovered by his research laboratory as the target gene and successfully constructed transgenic animals for screening anti-tumor drugs. He established a biological enzyme engineering technology system of immobilized enzymes, immobilized cells and genetically engineered bacteria, synthesized more than 10 chiral products and pharmaceutical intermediates, and formed industrialization. Among them, L-malic acid and L-aspartame Both amino acid and L-alanine have reached the annual production scale of 1,000 tons and achieved significant economic benefits. He has reached the international advanced level in molecular biology research of aging, and completed the project research on "The influence of aging on interleukin-2 gene expression and the effect of anti-aging Chinese medicine"; he revealed the relationship between IL-2, IL-3 and other gene expression and aging Relationship, this result has been applied by many laboratories.
Character anecdote
Wu Wutong has long advocated a modern pharmacy education model combining life sciences and chemistry, and established a comprehensive biopharmaceutical discipline system based on biochemistry and molecular biology, combining industrial microbiology and modern pharmacy, and presided over the establishment of the biopharmaceutical specialty And the School of Biopharmaceuticals. He has successively trained 2 post-doctoral students, 48 doctoral students and 57 master students. He has published more than 300 papers and written 14 monographs. It has applied for 15 national patents and has obtained 9 patent certificates. Served as the editor-in-chief of the professional core journal "Pharmaceutical Biotechnology", and also served as an editorial board member of various professional journals.
Awards
Wu Wutong has won the second prize of the National Spark Award, the first prize of the National Torch Excellent Project, the National Spiritual Civilization Construction "Five One Project" Award, 2 National Science and Technology Progress Awards, and 12 Ministry and Provincial Science Progress Awards. He was rated as a young and middle-aged expert with outstanding national contributions, a national model teacher, a national advanced individual in medicine, a national advanced individual of returned overseas Chinese and family members, a model worker in Jiangsu Province, an outstanding graduate tutor in Jiangsu Province, an outstanding Communist Party member model in Jiangsu Province, and an outstanding Jiangsu Province Subject leader, model worker in Nanjing. Enjoy the special government allowance of the State Council. In 1992, he was awarded the title of "Nanjing Science and Technology Hero" by the Nanjing Municipal Committee of the Communist Party of China and Nanjing Municipal People's Government.
Courses
Biopharmaceutical Research and Technology Progress (PhD student)
Cell Biology, Molecular Biology (Master student)
Biochemistry, Biopharmaceutical Technology, Introduction to Biopharmaceutics, Biotechnology Pharmacology, Biochemical Medicine, etc. (undergraduate)
Publish an article
Published more than 300 papers (more than 20 SCI) in core journals at home and abroad, and has obtained 13 invention patent certificates. Published "Modern Biochemical Pharmacy", "Biopharmaceutical Technology", "Biochemistry", "Biotechnology Pharmacology" "14 books and other textbooks.
"Research Progress on Maitake Polysaccharides" Bian Shan, Ye Boping, Xi Tao, Han Zhaoqing, Wu Wutong
"Molecular composition and hypoglycemic effect of Maitake polysaccharides" Ma Xun, Lei Hong, Wu Wutong
"Growth Dynamics and Computer Simulation of Maitake Deep Culture" Wang Weiyun, Wu Wutong
"Analysis and identification of the polysaccharide components of Maitake in liquid deep culture" Wang Weiyun, Wu Wutong
"Therapeutic effect of Maitake polysaccharide extract on type 2 diabetic mice" Ge Jiankang; Zhang Baipeng; Wu Wutong; Kong Yi
"Research Progress of Maitake and Its Pharmacological Effects" Wang Weiyun, Wu Wutong;
"Study on the Extraction and Activity of Maitake Polyphenols" Chen Xiangdong, Liu Xiaowen, Wu Wutong
"Isolation, Purification and Anti-tumor Activity of Low Molecular Weight Maitake Polysaccharide" Chen Xiangdong, Liu Xiaowen, Wu Wutong
"Glucose lowering activity of Maitake fruit body polysaccharide and its effect on α-glucosidase activity" Lei Hong, Wang Yi, Cai Liangliang, Wu Wutong
"Isolation, Purification and Physical and Chemical Properties of Maitake Mycelium Polysaccharide" Liu Xiaowen, Chen Xiangdong, Wu Wutong
"Enzymatic determination of β-glucose content in Maitake fruit body polysaccharide" Chen Guoguang, Meng Lei, Kong Yi, Yang Wan, Wu Wutong
