The invention discloses a Maitake polysaccharide F2 with hypoglycemic effect, a preparation method and application thereof. The preparation method of Maitake polysaccharide F2 was as follows: Maitake fruiting body was crushed, extracted with hot water, then filtered, ethanol was added to the filtrate to precipitate, and the precipitate was separated; The precipitation was carried out on a DEAE Sepharose fast flow column, and the fraction F1 was collected by equilibration with trishcl (10 mm, pH = 8.0); Then, the fraction F2 was obtained by elution with trishcl (10 mm, pH = 8.0) containing 0.1 M NaCl. The fraction F2 was concentrated under reduced pressure, dialyzed and dried to obtain Maitake polysaccharide F2. The invention separates a new Maitake polysaccharide F2 from Maitake, which has hypoglycemic activity and can be used for preparing drugs for treating diabetes. It lays a foundation for developing new drugs for treating diabetes mellitus (F2).
Brief introduction to Wu Qingping
Wu Qingping, academician of Chinese Academy of engineering, graduated from South China University of technology in 1999. He is now director of Guangdong Institute of Microbiology and doctoral supervisor. Deputy to the 13th National People's Congress, deputy director of China Society of food science and technology, deputy director of Technical Committee of China Beverage Industry Association, vice president of China Edible Fungi Association and executive deputy director of Expert Committee.
He has successively presided over and undertaken 42 national, provincial and ministerial level major scientific research projects; 28 achievements of international leading or international advanced level identified by provincial level; 135 national invention patents and utility model patents have been applied, of which 73 have been authorized; 13 national, provincial and bureau level science and technology awards were obtained, 10 national and local standards were formulated, including 8 national standards; 397 papers were published in national academic journals and academic conferences at home and abroad, 99 of which were included in SCI; He mainly participated in two books; It has won 2 second prizes of national science and technology progress, 5 first prizes and 1 second prize of provincial and ministerial level, 2 excellent patents of China and 1 Gold Patent Award of Guangdong Province.
In 2010, Academician Wu Qingping won the title of "outstanding contributor" of edible fungi industry and the title of national outstanding scientific and technological worker. In 2013, he was selected by Guangdong Province's "south Guangdong top 100" talent training project. In 2014, he won the first Guangdong inventor award, in 2015, he won the academician of Chinese Academy of engineering, and in 2017, he won the first south Guangdong outstanding contribution award.
Reference link:
https://zhuanli.tianyancha.com/0b54862c54d24d05b6e5347df86e112b
