During the SARS outbreak in 2003, all the military medical staff in Xiaotangshan were injected with thymopentin, resulting in zero infection.
After the new crown epidemic was confirmed, all the medical teams sent by the military also received thymopentin. In addition to military medical personnel, various local
The support medical team also tried their best to use thymopentin, and the infection rate of the medical staff in the final support was extremely low.
For many tumor patients, doctors also prescribed thymopentin to boost immunity after surgery, during radiotherapy and chemotherapy, and during convalescence…
Thymopentin is mainly used in primary and secondary immunodeficiency in clinical medicine, such as treatment of diffuse hepatitis B, critically ill hepatitis B, antiviral treatment, treatment of AIDS, etc. Adjuvant drugs for chemoradiotherapy. At this stage, there are many departments used in clinical medicine. Among them, 15.5% are used in oncology surgery and radiotherapy and chemotherapy. The second and third are medical oncology (12.7%) and respiratory medicine (9.2%).
Why do doctors and cancer patients choose thymopentin? Let's see what doctors and oncology patients have to say.
For doctors, the immunity of patients is extremely important, no matter during tumor treatment or out-of-hospital rehabilitation. It is obviously more reliable to choose a product with clear ingredients, safety, and significant curative effect and recommend it to patients rather than blindly choosing it on their own. , Thymopentin basically meets all these requirements; for patients, they are accustomed to using Thymopentin under the guidance of doctors, and the effect has always been good, even if they are not receiving treatment in the hospital, they are willing to prepare some Thymopentin continues to be used. After all, the improvement of immunity is something that requires long-term persistence. For them, the negligence of any link may cause irreversible consequences.
In addition, through clinical observation and the actual feedback effect of the majority of patients, the injection of thymopentin by tumor patients when the seasons change in autumn and winter or winter and spring can indeed effectively improve the patient's immunity, prevent colds, and avoid disease progression due to colds. At the same time, the injection of thymopentin in tumor patients after surgery, radiotherapy and chemotherapy, or during the convalescence period, can indeed play a good role in improving physical fitness. Whether it is for the consolidation of the overall treatment effect or the recovery of overall health, it has a great effect. irreplaceable role.
Even so, there are still some doubts about the use of thymopentin in cancer patients. Here, the author will explain the confusion for you one by one.
1. Is thymopentin safe?
Many people believe that pure natural is the best. But this statement is not necessarily true when it comes to drug use. thymosin
It is a biological product directly extracted from animal thymus, which is what we call a "pure natural drug", but because it is a mixture containing a variety of thymic hormones, the active ingredients are not clear, and there is no quantifiable quality control standard. Contains many macromolecular proteins. After these proteins are injected into the body, they are very likely to become antigens and cause allergic reactions. In severe cases, they can cause severe skin rash, high fever, dyspnea, anaphylactic shock, etc., so the safety factor is relatively low. Thymopentin is a key specific component in the body's thymus hormones. It is artificial, with accurate components, clear mechanism of action, relatively good safety, mild adverse reactions, and very rare allergic reactions. No skin test is required for use.
2. What is the difference between subcutaneous injection and intravenous drip of thymopentin?
Currently, thymopentin doses range from 1 mg to 50 mg for the treatment of tumors, immunocompromised and autoimmune diseases. Thymopentin can be injected subcutaneously, intramuscularly, or intravenously (infusion).
The specific route of administration of thymopentin depends on the type of disease. CD4+ T cells are sensitive to thymopentin, so subcutaneous injection is suitable for those with low CD4+ T cell function.
However, to stimulate CD8+ Ts cells, a higher concentration of thymopentin is required, and subcutaneous injection is difficult to achieve the concentration of stimulating CD8+ Ts cells. Therefore, when thymopentin is used to treat autoimmune diseases with suppressed Ts cell function (such as rheumatoid arthritis), slow intravenous administration is recommended, and the drug strength of this route of administration is 10 times that of subcutaneous injection.
3. Is the usage of thymopentin from different manufacturers the same?
In general, regular thymopentin includes Ou Ning, Guo Le, Hexin, Han Ning, Liertide, Taiputin and so on. Among these brands, as long as they are produced by regular manufacturers, they are all the same, after all, the ingredients are the same. However, the production process and excipients of thymopentin from different manufacturers are different. Although the specifications are all 1mg/piece, the route of administration is different. For example, thymopentin with a specification of 10mg/piece cannot be administered intravenously, but can only be injected intramuscularly or subcutaneously, while the thymopentin injection of Hainan Zhonghe Pharmaceutical (Hexin) can only be administered intramuscularly or intravenously, not subcutaneous injection.
4. What is thymopentin pre-filling needle? What's the difference with powder needles?
Prefilled Thymopentin Injection obtained the SFDA's production approval on December 15, 2005. It is a new dosage form launched by Zhonghe Pharmaceutical in China after the original domestic product and Xinfen injection. Pre-filled thymopentin injection is packaged in a unique pre-filled syringe, which is well-received by doctors and patients because of its dosage, convenience, safety, and pain relief. Unlike powder injection, prefilled thymopentin injection can be injected directly without dilution.
5. What are the side effects of thymopentin?
In clinical use, thymopentin has relatively few side effects. Individual patients may experience side effects such as nausea, fever, dizziness, chest tightness, and weakness, and a few patients occasionally experience drowsiness; if it is used by hepatitis B patients, it may lead to a temporary increase in ALT levels, such as You can continue to use the drug if there is no sign of liver failure.
Therefore, thymopentin is a relatively safe immunomodulatory drug. As long as patients use it under the guidance of a doctor, the side effects of thymopentin are relatively few.
6. Can thymopentin be used for a long time?
Generally speaking, long-term use of thymopentin does not cause significant side effects to the patient's body. Therefore, if the patient does not experience any adverse reactions during the application of thymopentin, it is possible to inject thymopentin for a long time. However, the essence of thymopentin is a short-chain protein, which may cause allergic reactions in patients, manifested as skin itching, edema, and even anaphylactic shock. At this time, the drug needs to be stopped in time. In addition, if a patient develops a series of autoimmune diseases due to excessively enhanced lymphocyte activity during the application of thymopentin, such as autoimmune myelitis, autoimmune nephritis, etc., thymopentin needs to be discontinued in time.
7. Can healthy people improve immunity by injecting thymopentin?
The human body is an organic unity, and the immune system of the body maintains a dynamic balance. Once this balance is broken, immune dysfunction, such as excessive or low levels, will occur. A healthy person blindly uses thymopentin and other drugs to enhance immune function, the body's immune function will be further enhanced or hyperactive, the body's homeostasis will be unbalanced, and eventually the body's immune function will be disordered and more susceptible to various diseases. However, if you are sure that your immune system is low, it is highly recommended to use thymopentin. If you are not sure whether your immune system is weakened, you can go to the hospital to do blood routine tests, lymphocyte subsets and other tests to comprehensively judge your immune function status. These drugs can be used in patients with chronic hepatitis B, immunocompromised people receiving viral vaccines and influenza vaccines. In addition, after surgery, radiotherapy and chemotherapy and other treatments, the immune function of cancer patients will be suppressed, and the immunity will be generally reduced. These drugs are used during the treatment and recovery period.
Thymopentin, a product with Chinese characteristics, has been used for more than 20 years as an adjuvant tumor therapy in clinical applications in my country. There are many different brands on the market, and in addition to injections, there are also oral medications. Cancer patients can consult their own clinicians or professionals according to their own conditions, in order to get the best advice and use effect.
