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Rebuilding immunity- the double line of immune activity

Source:chinamaitake Date:2020/12/24 17:28:12

Abstract:人体随着年龄的增加,免疫活性水平在不可避免的下降,同时,人体器官也在不断衰老,而衰老则会影响免疫细胞的数量和质量,让整个免疫系统功能下降。其次,老年人和慢性病患者的自我修复能力低,本身就免疫力低下,想要让免疫系统重新焕发活力,便需要更长的时间,而对于肿瘤患者尤其如此。 肿瘤患者,一方面需要合理的饮食与营养、保持健康的心理、适度的运动和顺应季节变化,以巩固免疫活性的基础;另一个方面则是要主动的提高自身免疫活性水平,适当的补充免疫刺激剂1-3,1-6 β-葡聚糖。这也是肿瘤患者提高免疫、增强免疫活性的“双行线”。

In the previous sharing, we learned about all aspects related to the immune system and immune activity, and fully understood that the tumor treatment process will bring greater damage to the body’s immunity, as well as diet and nutrition, exercise, healthy psychology, and personal The influence of living habits and seasons on our immune function and immune activity.

In fact, after we have learned so much, there is only one ultimate goal, and that is to better help cancer patients in recovery period prevent tumor recurrence and metastasis, and win this battle against cancer.

We all know that the recovery period of tumors refers to patients who are in the recovery period after surgery, chemotherapy, radiotherapy and other treatments. Due to the particularity of tumor cure standards, it is generally believed in medicine that the cure period for tumors is 5 years later, and some cancer types may be even longer, and even for patients who live with tumors, the rest of their lives belong to the recovery period, but Even after 5 years, we must still be highly vigilant against the possibility of recurrence, and at the same time, we must pay attention to prevent secondary tumors.

Therefore, for cancer patients, no matter how long the recovery period is, it is very necessary to pay attention to their own health and monitor their own immunity level. It can be said that the tumor rehabilitation period is a critical period of life and death. We should not only pay attention to the elimination of tumor foci, but also pay attention to the anti-cancer ability of the entire body. This requires patients to have long-term anti-cancer mental preparation during the rehabilitation stage, and even life-long anti-cancer.

According to relevant reports from CCTV, more than 90% of cancer patients' deaths are due to tumor recurrence and metastasis.

This is because given the current level of medical technology, it is impossible to completely eliminate the tumor cells of tumor patients. The objective existence of residual tumor cells is a cold fact in front of all tumor patients. Once tumor recurrence or metastasis occurs, it will be more troublesome, and the treatment process will also be more difficult. This will bring the pain of secondary treatment to our tumor patients. It is also possible that some treatment drugs will not be so sensitive. Reduced effectiveness, or even drug resistance, may cause a lot of trouble to the treatment and even get out of control.

Emotionally speaking, letting the patient suffer another hardship in the treatment process will also cause a serious blow to the patient's psychology.

Through the previous courses, we have learned that the occurrence, development and rehabilitation of tumors are closely related to our own immunity.

Every human body produces many cancer cells every day, just because the body's powerful immune system recognizes and destroys these bad cells, not everyone suffers from tumors.

To put it another way, all people suffering from tumors have abnormalities or defects in the immune system at one or more time points, allowing tumor cells to escape the trial and slowly develop and grow into tumors. This also shows that tumor patients themselves have the problem of weak immune function, coupled with the double blow of the tumor itself and tumor treatment to our immune system, the immunity of tumor patients is even weaker.

Therefore, the prevention of recurrence and metastasis of cancer patients during rehabilitation must improve the level of immune activity.

There is no doubt that paying attention to diet and nutrition, proper exercise, maintaining a healthy mental state, and adapting to seasonal changes are the basis for us to ensure the level of immune activity. But for cancer patients, just doing this is far from enough. Because these are only the basis for ensuring our normal immune function, cancer patients must also find ways to improve their own immune activity levels.

For this reason, we set our sights on polysaccharides, a natural product that exists in large quantities in nature.

Polysaccharide compounds are widely present in animals, plants and microorganisms. They are one of the important components of living substances. They participate in the regulation of cell structure and physiological processes, and have an irreplaceable effect on the immune function of the human body. For example, the transmission and perception of information between immune cells, cell transformation, division, and regeneration all require the participation of polysaccharides.

In the topic "The Wisdom of Immunity", we found that in the secret of Japanese longevity, one of the most important points is that the Japanese have long included edible fungi in their daily diet to supplement the natural β-glucan in polysaccharides. . Beta-glucan is a natural supplement that promotes immune activity. Japanese people eat this special nutrition whether they eat a lot of fungus and mushrooms in their diet or daily health products such as fungal extracts.

β-glucan is widely found in various edible fungi, such as Agaricus blazei, shiitake mushroom, Ganoderma lucidum, Maitake. The human body only has α-amylase and cannot digest β-glucan, so β-glucan does not enter the human body. It will be digested and decomposed, but will bind to receptors on the cell membrane to produce pharmacological activity. For example, β-glucan binds to receptors outside of macrophages, thereby activating macrophages and affecting the production of cytokines, playing an important role in fighting cancer cells and infections.

In addition, the structure of β-glucan is diversified. According to the different types of linear chains connected by glycosidic bonds, there are mainly β-(1,3), β-(1,4), β-(1,6), etc. Several forms. With different molecular weight, branching degree, conformation and intramolecular interconnection, its anti-tumor activity and the mechanism of action as biological response modifiers (BRMs) vary greatly, and even have opposite results.

Just like when we open a lock with a key, you can't open the lock with unmatched keys no matter how hard you try. Studies have shown that only 1-3,1-6 β-glucan can better combine with immune cells, and can better improve the ability of immune cell signal transduction, thereby activating and promoting immune activity. Therefore, β-(1,3) bond glucan has immunostimulatory activity and anti-tumor effect.

Unfortunately, the intake of β-glucan is seriously inadequate in our daily diet. Although my country is the country with the largest production of edible fungi, because of its large population base, per capita resources are extremely small, and edible fungi have not been routinely eaten. They don't eat many times throughout the year, let alone additional supplements.

Japan, as the first country in the world to study edible fungi, used Maitake polysaccharide as an antidote to the sequelae of the atomic bomb after World War II. Since then, they have applied edible fungi to many aspects of daily life. Therefore, Japan can It is not surprising that it has been the world's longest-lived country for 20 consecutive years.

Therefore, in addition to cultivating good living and eating habits, the elderly and patients with chronic diseases should appropriately supplement the immune activity promoter β-glucan compared to the young and healthy people.

Because, as the human body ages, the level of immune activity will inevitably decline. At the same time, human organs are also aging, and aging will affect the number and quality of immune cells and reduce the function of the entire immune system. Secondly, the elderly and patients with chronic diseases have low self-repair ability and low immunity. It takes longer to rejuvenate the immune system, especially for cancer patients.

Cancer patients, on the one hand, need a reasonable diet and nutrition, maintain a healthy mind, moderate exercise and adapt to seasonal changes to consolidate the basis of immune activity; on the other hand, they must actively increase the level of autoimmune activity and supplement immunity appropriately. Stimulant 1-3, 1-6 β-glucan. This is also a "double line" for tumor patients to improve immunity and enhance immune activity.

This is the end of the "Building of Immunity" series. Thank you for your attention.

Reference:

《肿瘤康复期的治疗》张秉琪,张欣,安煜致 编著  人民军医出版社P2-4

https://tv.cctv.com/2013/12/03/VIDE1386079745731321.shtml?spm=C55924871139.PKgX4CXWWE68.0.0

https://www.sohu.com/a/250763196_781823

https://baike.baidu.com/item/%E8%91%A1%E8%81%9A%E7%B3%96

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