In the last course, we fully understood the secret of longevity of Japanese people. Thanks to balanced dietary habits and good living habits, the Japanese are able to maintain a long-term immune activity level, thus seizing one of the lifebloods of health and longevity. In this course, we will focus on the relationship between immunity and health.
I believe that the first reaction of many people after illness is to see a doctor, and they all want to find the best doctor. In fact, as early as more than 2,000 years ago, Hippocrates, the father of modern medicine, pointed out: The best doctor is yourself, in the human body, he is the healthy immune system. The battle between the immune system and disease is a very complex process. In this war, the human body’s immune system coordinated and cooperated with each other to deal with problems appropriately.
It can be said that human beings are always in a state of resistance when facing the attack of pathogenic sources, and immunity is our primary line of defense.
And these pathogenic sources mainly include two major aspects:
One is the microscopic aspect, exogenous such as bacteria, viruses, etc., endogenous such as DNA mutations, etc. Once our immune system can not resist, these pathogenic sources will cause us to develop diseases.
On the other hand, it is macroscopic, such as age, nutrition, lifestyle, psychological factors, etc. We all know that as we age, our body functions decrease. For example, improper nutritional intake will lead to malnutrition, and people will appear thin or obese. Others often stay up late and are in poor spirits and suffer from diseases. What's more, many people are like Lin Daiyu who are depressed and unhappy every day. Many problems come.
There is no doubt that in the face of so many threats, once our body's own healthy immune system becomes unhealthy, our body will suffer from many diseases. This is the case for many middle-aged and elderly people. The immune system collapses, and people also collapse.
Perhaps in today's information age, everyone is familiar with the word immunity. Everyone's brain is filled with many new words, such as "antigens, antibodies, antigen presentation, killer T cells, dendritic cells, immunotherapy..." and so on, but immunity is a very complex system.
We just said that if we want to use a vivid metaphor to describe the immune system, it is the regular army that guards our health, the absolute trump card force.
The command center of this army is our central immune organ, including bone marrow and thymus. Here, hematopoietic stem cells will differentiate and develop into various immune cells, including NK cells, macrophages, T cells, B cells, antigen presenting cells, dendritic cells, etc., according to the signals sent by the body to the center. It's like the major military academies have cultivated all kinds of military talents. Some of them are on the front lines, some are liaison officers, and some may be responsible for launching missiles.
Immune cells can produce many cytokines, such as interleukins, interferons, colony stimulating factor, tumor necrosis factor, etc. These cytokines are like weapons made by immune cells to enhance their combat effectiveness.
Differentiated and mature immune cells will follow our two major circulatory systems, lymphatic circulation and blood circulation, to our spleen, lymph nodes throughout the body, and mucosal-related lymphoid tissues, including the respiratory tract, gastrointestinal tract, and urogenital The epidermal layer, lamina propria and some organized mucosal tissues, such as appendix and tonsils, are camped in them. Once they are stimulated by external sources, they will fight at any time! These parts are called peripheral immune organs. The surrounding immune organs are places where immune cells settle and work, just like battlefields where the immune response is completed.
The huge immune system, in an orderly manner, protects our body day after day. A healthy immune system, when the wind and waves are calm, most departments are training hard, replenishing energy; there will also be some immune cells, always in an active state, just like a competent inspector, paying attention to every In a corner, until a certain moment, the invasion of pathogens occurred.
Once an invasion occurs, the immune system will respond quickly and quickly identify these invading criminals from the sea of thousands of cells. Healthy cells have their own passes, and immune cells will recognize them and will not attack them. The invading pathogens such as bacteria and viruses, without such signs, will be quickly recognized by the patrolling immune cells, and the signal will be quickly transmitted back to the base camp, and the battle will begin.
A healthy immune system can not only identify invaders, but also traitors in the body. In our body, mutations happen all the time, and there are many cells that undergo mutations, such as tumor cells, which are also quickly picked up by the immune system. The tumor is recognized and eliminated. As long as the immune system can respond in time every time, the tumor will not occur.
When the signal is transmitted, a healthy immune system will quickly give feedback. The first challenge is our basic immunity. What is basic immunity? Simply put, we are born for humans, and natural selection is reserved for us. immune system. It is non-specific and starts quickly. Generally speaking, within 0-4 hours of infection, our basic immunity will start quickly.
Usually, the basic immune response is enough to settle these abnormal invaders. However, in some cases, the number of invaders or traitors in the body is extremely large or very cunning, and the basic immunity cannot cope with it. Then, the body will activate our elite troops. , Adaptive immunity, also called special immunity. The adaptive immune response takes a long time to initiate, usually 96 hours after the infection occurs. The adaptive immune response system mainly includes two types of lymphocytes, lymphoid T cells and lymphoid B cells, which are involved in cellular immunity and humoral immunity respectively. Response type.
Under the combined action of basic immunity and adaptive immunity, a healthy immune system usually wins. At this time, the battle is not over. There is still a very important task, which is memory. Our immune system is strong because it is very smart and hardworking. After a battle, the immune cells responsible for memory work will accurately record the appearance of the enemy. Once the same enemy invades again, the immune system will quickly activate. Channel, quickly and efficiently destroy the enemy, we can understand this memory as resistance.
When this tense battle ended perfectly, the healthy immune system returned to the state of daily methodical inspection and training, maintaining good adjustment capabilities, maintaining the stability of our internal environment, and maintaining keen awareness and efficiency. Combat power, this is the most important daily routine for a healthy immune system.
We can summarize the three major missions of the immune system. One is to keep an eye on the bad guys, the other is to defend against attacks, and the third is to eliminate the enemy. So since our immune system is the enemy of bacteria, viruses, and rebel cells, why do humans still have so many diseases? Even the occurrence of tumors? Think about it, if a gust of wind blows and others are fine, but you have a headache and sneezes; it is also raining without an umbrella, and others will be fine if they change clothes, but you have a cold and a fever... At this time you have to think about whether it is your own The immune system is not strong enough.
Then the next course will share with you the relationship between the level of immune system activity and human health.
References:
https://baike.baidu.com/item/%E5%85%8D%E7%96%AB%E7%B3%BB%E7%BB%9F/668170?fr=aladdin
