Abstract:β-葡聚糖广泛存在各种食用真菌中,如姬松茸、香菇、灵芝、灰树花中,人体只有α淀粉酶,无法消化β-葡聚糖,所以β-葡聚糖进入人体后不会被消化、分解,而是和胞膜上的受体结合,进而产生药理活性。
What is immunity? What are the signs of reduced immunity? How can we improve immunity? This series of problems bother each of us, and this is the original intention of our "Wisdom of Immunity". In the previous course, we learned about the past and present of the human immune system. She is the primary line of defense to protect our health and protects us from the wind and rain all the time. But once there is a problem with the defense line of immunity, our physical health will have problems, and we will suffer from various diseases, especially tumors.
We know that as long as we are still alive and in this world, we will inevitably face a variety of pathogens every day. We all hope that our immune system will be a swiftly responsive, well-equipped, and combat-powered king's division, rather than a grass-roots team that is overwhelmed and reluctant to fight. However, we also know that to maintain a healthy immune system and build an invincible elite force requires our own perseverance and training.
We need to start from two aspects. The first is to "grasp the basics" and the second is to "grasp the vitality", that is, to "grasp the two basic points."
First, we need to grasp the basics, we need to do 4 things.
First, insist on exercising moderately every day. Life lies in exercise. Exercise is like an immunostimulant, which stimulates our immune system to respond and puts our immune system in a state of daily training and exercise.
Second, ensure adequate daily nutritional intake. Reasonable and balanced nutrition is the logistical support of the army of our immune system. Without high-quality nutritional intake, our soldiers will not have sufficient supplies of materials, our weapons and equipment will be unable to synthesize, and our army will not have the slightest combat effectiveness.
Third, maintain a happy mood and a healthy lifestyle. Bad moods and bad habits in daily life threaten our health all the time, such as depression, insomnia, drinking, and smoking can easily cause our immune damage.
Fourth, regular physical examinations. Regular physical examinations can help us achieve early detection and early intervention, allowing us to constantly monitor our immune system health.
Secondly, to focus on activity, we need to do two things.
Through the first lesson, we can learn from the Japanese secrets of longevity, namely exercise, nutrition, and eating fungi. Here, the first thing we can do is to incorporate edible fungi into our daily diet, and the second thing is to supplement the appropriate amount of immune booster β-glucan daily.
Edible fungus β-glucan, which is rich in edible fungi, is a natural aid to promote immune activity. Japanese people eat this kind of health products whether they eat a lot of fungi and mushrooms in their diet or daily fungus extracts. Special nutrition.
When it comes to sugar, many people may think of the sugar they usually eat, and even immediately think of diabetes, so they are resistant to things with the word "sugar".
But what you don't know is that all kinds of sugars we eat in our daily life are alpha polysaccharides. Through digestion, they are transformed into glucose needed by the human body, which then supplements energy for our human body. β-glucan is widely found in various edible fungi, such as Agaricus blazei, shiitake mushroom, Ganoderma lucidum, Maitake. The human body only has α-amylase and cannot digest β-glucan, so β-glucan does not enter the human body. It will be digested and decomposed, but will bind to receptors on the cell membrane to produce pharmacological activity. For example, β-glucan binds to receptors outside of macrophages, thereby activating macrophages and affecting the production of cytokines, playing an important role in fighting cancer cells and infections.
In addition, the structure of β-glucan is diversified. According to the different types of linear chains connected by glycosidic bonds, there are mainly β-(1,3), β-(1,4), β-(1,6), etc. Several forms. With the difference in molecular weight, branching degree, conformation and intramolecular interconnection, its anti-tumor activity and the mechanism of action as biological response modifiers (BRMs) vary greatly, and even have opposite results.
Just like when we open a lock with a key, you can't open the lock with unmatched keys no matter how hard you try. Current studies have found that only β-(1,3) bonds have immunostimulatory activity and anti-tumor effects. The key that can open the door to our immune lock is natural 1-3,1-6 β-glucan. Studies have shown that only 1-3,1-6 β-glucan can better combine with immune cells, and can also better improve the ability of immune cell signal transduction, thereby activating and promoting immune activity.
The so-called signal transmission, just like in a war, the military order is passed down one by one through the soldiers. If all are communicated in place, the military order will be well implemented. On the contrary, if there is a recruit in the middle who has poor response ability, the military order cannot continue. Good conduction will cause our immune signal to be interrupted, and the result must be bad.
From this, we can clearly see how β-glucan plays a role in our immune system.
Unfortunately, the intake of β-glucan is seriously inadequate in our daily diet. Although my country is the country with the largest production of edible fungi, because of its large population base, the per capita resources are extremely small, and edible fungi have not been routinely eaten, and the number of times eaten is small, let alone additional supplements.
Japan, as the first country in the world to study edible fungi, after the end of World War II, they used Maitake polysaccharide as an antidote to the sequelae of the atomic bomb. Since then, they have applied edible fungi to many aspects of daily life. Therefore, Japan can It is not surprising that it has been the world's longest-lived country for 20 consecutive years.
Returning to the topic of longevity again, in fact, everyone knows that no matter how many congratulations you have heard of "longevity one hundred years old", there is no practical use. Only by using your own efforts to protect the immune system and create your own health and longevity is practical. of.
Because, as any of us ages, the level of immune activity will inevitably decline. At the same time, our organs are also aging, and aging will seriously affect the number and quality of our immune cells, causing the entire immune system to fall into Dilemma. Secondly, the elderly and patients with chronic diseases have low self-repair ability, and their immunity is low. It takes a longer cycle to rejuvenate the immune system as it should. Therefore, we need the help of foreign aid, an "immune booster". We know that β-glucan with 1-3,1-6 structure is a high-quality immune booster. Therefore, appropriate supplementation of 1-3,1-6β glucan according to your own situation will help improve immunity.
This is the end of the "Wisdom of Immunity" series. Thank you for your attention.
https://baike.baidu.com/item/%E5%A4%9A%E7%B3%96
https://baike.baidu.com/item/%E8%91%A1%E8%81%9A%E7%B3%96
《β-葡聚糖的特性及其对动物免疫功能的调节》陈昌福,陈萱,陈超然,梁运祥
https://www.ixueshu.com/document/fd8b4b6c478a7b1e.html
《灰树花菌丝体β-葡聚糖的制备及其免疫调节作用》王宝琴,徐泽平,王文秀
https://www.ixueshu.com/document/1dda39cabca2c5f186fda420f3e91c0a318947a18e7f9386.html
《β-葡聚糖研究进展》汲晨锋,郭守东,申奥
https://www.ixueshu.com/document/6880d4cbb106d1b5c06434b3ab640fa3318947a18e7f9386.html
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