Introduction: selenium is an essential trace element for human body, which is very important for human life activities. It participates in the synthesis of a variety of selenium containing enzymes and selenium containing proteins in human body, and has a variety of biological functions. For most people, adequate selenium supplementation is of positive significance to maintain good health and prevent some diseases. Cardiovascular and cerebrovascular diseases are the number one killer of human health.
According to incomplete statistics, at present, the number of people dying of cardiovascular and cerebrovascular diseases in the world every year is as high as 15million, ranking first among various causes of death.
Cardiovascular and cerebrovascular diseases mainly include cardiovascular and cerebrovascular diseases:
Cardiovascular disease
Common cardiovascular diseases include hypertensive heart disease, coronary atherosclerotic heart disease, etc. Common symptoms include: palpitation, shortness of breath, sitting upright breathing, paroxysmal dyspnea at night, compression or contraction pain behind the sternum, chest tightness, edema, cyanosis, syncope, cough, hemoptysis, weakness, belching, epigastric pain, nausea, vomiting; Left back pain, left arm pain, etc.
Cerebrovascular disease
Cerebrovascular disease is a group of diseases that occur in brain blood vessels and cause brain tissue damage due to intracranial blood circulation disorders. "Cerebrovascular accident", "stroke" and "stroke" in our life all belong to cerebrovascular diseases. Clinically, most of the acute diseases are middle-aged and elderly patients.
There may be hemiplegia, hemiparesis, hemiblindness, aphasia; Or cross paralysis, cross sensory disturbance, external ophthalmoplegia, nystagmus, dysphagia, ataxia, vertigo, etc; Or limb weakness, numbness, facial, upper and lower limb sensory disorders; Unilateral limb movement is not flexible; Language barrier, not speaking neatly; Memory decline; The object is suddenly unclear; Or inflexible eye rotation; Urinary incontinence; Imbalance of balance and unstable standing; Disturbance of consciousness; Headache or nausea and vomiting; Dizziness, tinnitus, etc.
How to prevent cardiovascular and cerebrovascular diseases?
The secret of preventing cardiovascular and cerebrovascular diseases lies in "reasonable diet, moderate exercise, smoking cessation and alcohol restriction, less salt and psychological balance".
People with high disease incidence should pay attention to eating more coarse grains, vegetables, fruits and other fiber rich foods, eat more fish and fish oil products to regulate blood lipids, eat more bean products, and appropriately reduce the intake of fat and cholesterol.
Don't drink cold water or eat cold food. It's best to drink a cup of warm water before morning exercise or going to bed at night, so as to dilute the blood and ensure that the blood vessels are relatively unblocked, so as to reduce the onset of disease. Keep exercising continuously and gently, and avoid exercising when the temperature is cold in the morning. We must quit smoking and control drinking, maintain mental health and optimism, and try to be less angry.
Selenium - blood scavenger
As an important component of glutathione peroxidase (GSH PX), the most important antioxidant enzyme in human body, selenium is closely related to cardiovascular and cerebrovascular diseases.
For example, the incidence of cardiovascular and cerebrovascular diseases in high selenium areas such as the United States and Finland is significantly lower than that in low selenium areas; Keshan disease (an endemic cardiomyopathy) found in China also found that selenium deficiency is one of the important causes, and the incidence rate of Keshan disease in high-risk areas decreased significantly after selenium supplementation.
Scientific research has also proved that selenium mainly affects the occurrence and development of cardiovascular and cerebrovascular diseases through the following four functions.
Remove lipid peroxide
The occurrence of cardiovascular and cerebrovascular diseases is related to excessive lipid peroxides in the body. Excessive lipid peroxide can damage various cell biofilms through oxidation, leading to cell dysfunction and even cell death. If continuous oxidation can cause atherosclerosis and myocardial fibrosis in blood vessels, it can eventually develop into coronary heart disease and hypertension, cerebral infarction, renal artery stenosis, arterial occlusion and so on.
Role: GSH PX composed of selenium can play a powerful antioxidant role, reduce the concentration of various lipid peroxides, protect the biofilm of vascular endothelial cells and myocardial cells, prevent atherosclerosis and myocardial cell death and fibrosis, and reduce the incidence of thrombosis.
Regulating blood lipids
Hypercholesterolemia and hypertriglyceridemia are one of the important causes of cardiovascular and cerebrovascular diseases. Increased blood cholesterol, especially low density lipoprotein cholesterol (LDL CH), can lead to increased blood viscosity, the formation of atherosclerotic plaque, and cause a variety of cardiovascular diseases, including coronary heart disease.
Function: Selenium prevents the oxidation of LDL CH and further prevents the formation of atherosclerotic plaque through its strong antioxidant effect. Studies have confirmed that selenium supplementation can improve the activity of GSH Px, reduce triglycerides and LDL Ch in blood, increase high density lipoprotein cholesterol (HDL CH), and reduce blood viscosity.
Scavenging free radicals
The aging of human body is related to the damage of cell biofilm by free radicals. With the growth of age, free radicals increase, damaging vascular wall cells and cardiomyocytes, leading to vascular sclerosis and cardiomyocyte degeneration and death, resulting in senile cardiovascular disease.
Function: selenium is a strong antioxidant, which can help clear free radicals, prevent vascular and myocardial aging, and prevent myocardial infarction, stroke and other cardiovascular and cerebrovascular diseases to a certain extent.
It can be seen that selenium has a certain protective effect on the cardiovascular and cerebrovascular system. Studies have shown that the blood selenium level and antioxidant function of people over 50 years old decline with age, and the possibility of cardiovascular and cerebrovascular diseases is higher than that of the general population. For this reason, experts suggest that even healthy people should pay attention to the daily intake of selenium.
The Chinese Nutrition Society recommends that normal adults need to supplement 50-250 micrograms of selenium every day, while patients with cardiovascular and cerebrovascular diseases need to increase the amount of selenium supplement to 250-300 micrograms.
Article source:
https://weibo.com/ttarticle/p/show?id=2309404647208715682127
