Cold-water extracts of Grifola frondosa and its purified active fraction inhibit hepatocellular carcinoma in vitro and in vivo

Title：Cold-water extracts of Grifola frondosa and its purified active fraction inhibit hepatocellular carcinoma in vitro and in vivo

Author：Chia-Hung Lin  1 , Ching-Yao Chang  2 , Kuan-Rong Lee  3 , Hui-Ju Lin  4 , Wu-Chou Lin  5 , Ter-Hsin Chen  6 , Lei Wan

Research institutions：

1 Institute of Molecular Medicine, National Tsing Hua University, Hsinchu 30013, Taiwan; 

2 Department of Biotechnology, Asia University,Taichung 41354, Taiwan; 

3 Department of Ophthalmology, China Medical University Hospital, Taichung 40402, Taiwan; 

4 School of Chinese Medicine, China Medical University, Taichung 40402, Taiwan; 

5 Department of Gynecology, China Medical University Hospital,Taichung 40402, Taiwan; 

6 Graduate Institute of Veterinary Pathobiology, College of Veterinary Medicine, National Chung Hsing University,Taichung 40227, Taiwan

Key words：Grifola frondosa, bioactive, apoptosis, autophagy, cell cycle, Hep3B

Published journal：Exp Biol Med (Maywood)，2016，241(13):1374-1385.     

Literature reading, download link：

1 https://www.zhangqiaokeyan.com/academic-journal-foreign-pmc_experimental-biology-and-medicine_thesis/040001419388.html

2 http://dx.doi.org/10.1177/1535370216640149

3 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4994922/pdf/10.1177_1535370216640149.pdf

4 http://europepmc.org/abstract/MED/27013543

5 https://www.researchgate.net/publication/299413919_Cold-water_extracts_of_Grifola_frondosa_and_its_purified_active_fraction_inhibit_hepatocellular_carcinoma_in_vitro_and_in_vivo

6 https://www.pubfacts.com/detail/27013543/Cold-water-extracts-of-Grifola-frondosa-and-its-purified-active-fraction-inhibit-hepatocellular-carc

7 http://www.onacademic.com/detail/journal_1000038764575810_7c27.html

8 https://www.mysciencework.com/publication/show/coldwater-extracts-grifola-frondosa-its-purified-active-fraction-inhibit-hepatocellular-carcinoma-vitro-vivo-3eba5cc2?search=1