Maitake is a edible and medicinal mushroom with good health care and high medicinal value. In recent years, as a kind of advanced health food, it is used for the prevention and treatment of diabetes.
Maitake can reduce blood sugar
It was found that the crude extract of Maitake could reduce the fasting blood glucose of diabetes mice by 57.8%. GFE from Maitake mycelia may be mediated by NF- κ B related signal pathway to achieve its hypoglycemic effect. α- Glucosidase can induce postprandial hyperglycemia and other diseases. Maitake polysaccharide with a concentration of 0.4mg • ml-1 can inhibit α- The IC50 value of glucosidase activity is 0.424mg • ml-1, which plays an active role in the treatment of diabetes. Maitake polysaccharide can enhance the synthesis and excretion of bile acids in the liver and achieve the effect of reducing blood glucose by regulating intestinal flora, regulating the mRNA expression of genes related to liver glucose and lipid metabolism and the expression level of genes related to cholesterol metabolism.
Maitake can reduce blood lipids
There is a close relationship between glucose metabolism and lipid metabolism in animals. When hyperglycemia occurs, it will also lead to hyperlipidemia. Therefore, correcting the disorder of glucose and lipid metabolism is an important means to treat diabetes and its complications. Maitake mycelium polysaccharide can reduce blood glucose and blood lipid in diabetes. The results showed that Maitake mycelium polysaccharide could significantly reduce blood glucose, triglyceride, cholesterol and serum LDL-C in diabetes mice.
Effect of Maitake on insulin
Maitake can reduce insulin resistance and enhance the sensitivity of human body to insulin. The level of insulin in plasma of experimental mice was slightly increased after oral administration of Maitake fruit body dry powder. Many clinical trials in the United States and Japan have found that SX fraction of Maitake extract can effectively repair insulin, bringing good news to many patients with type I and type II diabetes. Maitake polysaccharide can improve insulin resistance by regulating related enzymes. Maitake polysaccharide gfp-n can improve hepatic insulin resistance by activating IRS1, PI3K and glut, regulating irs1/pi3k and JNK signaling pathways.
Suitable population
It is suitable for general diabetics, and also suitable for children, women, and patients with cancer, low immunity, liver disease, hypertension, arteriosclerosis, cerebral thrombosis, obesity, edema, beriberi, adverse urination, etc.
